Publications & Presentations
September 6th, 2023
Alex Sherman presented New Insights from “Old” Data: Combining Pooled Data from Clinical Trials and RWD at BioTechX in Santa Clara, CA
July 17th, 2023
Alex Berger, Matteo Locatelli, Ximena Arcila-Londono, Ghazala Hayat, Nicholas Olney, James Wymer, Kelly Gwathmey, Christian Lunetta, Terry Heiman-Patterson, Senda Ajroud-Driss, Eric A. Macklin, Marie-Abèle Bind, Kimberly Goslin, Tamela Stuchiner, Lauren Brown, Tracy Bazan, Tyler Regan, Ashley Adamo, Valerie Ferment, Carly Schroeder, Megan Somers, Georgios Manousakis, Kenneth Faulconer, Ervin Sinani, Julia Mirochnick, Hong Yu, Alexander V. Sherman, David Walk & The Pooled Resource Open-Access ALS Clinical Trials Consortium (2023) The natural history of ALS: Baseline characteristics from a multicenter clinical cohort, Amyotrophic Lateral Sclerosis and Frontotemporal Degeneration, DOI: 10.1080/21678421.2023.2232812
July 13th, 2023
ENCALS, Barcelona Spain, Matteo Locatelli. Methods to test for causality and mortality in Amyotrophic Lateral Sclerosis: A Real-World Data example using MiToS Staging. https://www.encals.eu/wp-content/uploads/2023/05/Draft-Programme-ENCALS-Barcelona-2023-V1.pdf
July 13th, 2023
ENCALS, Barcelona Spain, Alex Berger. Analyzing the use of statins in people living ALS using real-world data. https://www.encals.eu/wp-content/uploads/2023/05/Draft-Programme-ENCALS-Barcelona-2023-V1.pdf
July 13th, 2023
Safety and Activity of Anti-CD14 Antibody IC14 (atibuclimab) in ALS: Experience with an Expanded Access Protocol Dario Gelevski, Grace Addy, Caroline Cohen, Margot Rohrer, Aimee Roderick, Erin Clampffer, Allison Winter, Judith Carey, Jennifer Scalia, Megan Yerton, Harli Weber, Michael Doyle, Neil Parikh, Geli Kane, Amy Ellrodt, Katherine Burke, Derek D’Agostino, Ervin Sinani, Hong Yu, Alexander Sherman, Jan Agosti, Garry Redlich, Patrick Charmley, David Crowe, Mark Appleby, Brian Ziegelaar, Katherine Hanus, Zhenhua Li, Johnna Varghese, Suma Babu, Katharine Nicholson, Sarah Luppino, James Berry, Clare Baecher-Allan Sabrina Paganoni, Merit Cudkowicz
May 18th, 2023
Bio-IT, Boston MA. Matteo Locatelli. Statistical Methods and Techniques to Develop Meaningful Insights from Datasets; Real World Data as a Control Group. https://www.bio-itworldexpo.com/bioinformatics
May 17th, 2023
ALS Drug Discovery Summit, Boston MA. Ian Wynyard, Alex Berger. Data Harmonization for ALS/MND: Data Lake.
May 17th, 2023
Bio-IT, Boston MA. Alexander V. Sherman. Tools to Access and Interact with Publicly-Available Data and Drive Innovation in Clinical Research; Utilization of Pooled RCT Datasets and RWD in Registration Trials. https://www.bio-itworldexpo.com/clinical-translational-informatics
May 16th, 2023
ALS Drug Discovery Summit, Boston MA. Alexander V. Sherman. Optimizing ALS Clinical Trials to Incorporate the Evolving Standard of Care & Standardize Trial Design. https://www.als-drug-development.com/about/about-event/
April 26th, 2023
American Academy of Neurology, Boston MA. Matteo Locatelli, Alex Berger, Alexander V Sherman. Real World Data as a control group, an ALS case study. https://www.aan.com/MSA/Public/Events/AbstractDetails/54300
April 23rd, 2023
American Academy of Neurology, Boston MA. Alex Berger, David Walk, Matteo Locatelli, Alexander V. Sherman. Survival Analysis Methods in Natural History Studies. https://www.aan.com/MSA/Public/Events/AbstractDetails/53637
January 27th, 2023
Precision Medicine World Conference. San Francisco, CA. AI/ML Applications for Patient Outcomes Prediction and Clinical Decision Support. Alexander V. Sherman.
December 7th, 2022
33rd International ALS/MND Symposium [Virtual]. EPI-09 Kidney Function (eGFR MDRD) in ALS Patients. Mr. Matteo Locatelli. https://symposium.mndassociation.org/wp-content/uploads/2022/11/PROGRAMME.pdf
December 7th, 2022
33rd International ALS/MND Symposium [Virtual]. EPI-02 Lessons Learned from Survival Modeling in an Expanded Access Protocol. Mr. Alex Berger. https://symposium.mndassociation.org/wp-content/uploads/2022/11/PROGRAMME.pdf
November 9th, 2022
BioTechX Conference, Basel Switzerland. How the lines between health systems and pharma should be redrawn to allow patient data flow: The platformization of clinical data Alexander V. Sherman
November 1st, 2022
21st Annual NEALS (Northeast ALS Consortium) Meeting, Clearwater FL. Legal and Regulatory Framework for Data Sharing. Natalia Tarasenko, Alexander Sherman https://onlinelibrary.wiley.com/doi/abs/10.1002/mus.27729
November 1st, 2022
21st Annual NEALS (Northeast ALS Consortium) Meeting, Clearwater FL. The PRO-ACT Platform and its Impact on ALS Research Igor Katsovskiy, Erin Sinani, Prasha Vigneswaran, Matteo Locatelli, Alex Berger, Ian Wynyard, Natalia Tarasenko, Alexander V. Sherman https://onlinelibrary.wiley.com/doi/abs/10.1002/mus.27729
November 1st, 2022
21st Annual NEALS (Northeast ALS Consortium) Meeting, Clearwater FL. The Impact of Hyperlipidemia on Survival Prognosis for Patients with Amyotrophic Lateral Sclerosis Alex Berger, Matteo Locatelli, Christian Lunetta, David Walk, Alexander V. Sherman https://onlinelibrary.wiley.com/doi/abs/10.1002/mus.27729
November 1st, 2022
21st Annual NEALS (Northeast ALS Consortium) Meeting, Clearwater FL. A Public-Private Process to Share Data Without Exposing PII. Alex Berger, Matteo Locatelli, Ervin Sinani, Jaime Raymond, Paul Mehta, Igor Katsovskiy, Theodore Larson, Kevin Horton, Alexander V. Sherman https://onlinelibrary.wiley.com/doi/abs/10.1002/mus.27729
June 1st, 2022
ENCALS Meeting, Edinburgh Scotland. Validation of ENCALS ALS survival model on US Population. Alex Berger, Ruben van Eijk, Ervin Sinani, Alexander V. Sherman. https://www.encals.eu/wp-content/uploads/2022/05/Programme_ENCALS2022_31May.pdf
May 3rd, 2022
American Academy of Neurology, Seattle WA. Alex Berger, Ervin Sinani, Igor Katsovskiy, Jaime Raymond, Derek D’Agostino, Natalia Tarasenko, Paul Mehta, Alexander V. Sherman. Public-Private Collaboration in ALS Research by GUID Utilization Paves the Road to Patient-Centric Precision Research in Neurological Diseases (P4-5.001). Presented at the American Academy of Neurology, May 3, 2022. https://www.cdc.gov/als/ALSAbstracts.html
May 14th, 2013
Alexander V. Sherman, Amelie K. Gubitz, Ammar Al-Chalabi, Richard Bedlack, James Berry, Robin Conwit, Brent T. Harris, D. Kevin Horton, Petra Kaufmann, Melanie L. Leitner, Robert Miller, Jeremy Shefner, Jean Paul Vonsattel & Hiroshi Mitsumoto (2013) Infrastructure resources for clinical research in amyotrophic lateral sclerosis, Amyotrophic Lateral Sclerosis and Frontotemporal Degeneration, 14:sup1, 53-61, DOI: 10.3109/21678421.2013.779058